Peyton and Eli Manning didn't miss a beat on the season premiere of the "ManningCast" during Week 1 of "Monday Night Football."

The biggest topic of the night was the debut of Aaron Rodgers with the New York Jets against Josh Allen and the Buffalo Bills at MetLife Stadium. Though Rodgers was sidelined by an early injury, the duo still had plenty to talk about.

The Mannings were joined by tennis legend John McEnroe and former NFL quarterback Ryan Fitzpatrick, who spent two seasons with the Jets.

Here are the best "ManningCast" moments from Monday night:

Jets walk off win leaves Peyton, Eli and Ryan Fitzpatrick speechless What a way to end the first ManningCast of the season. pic.twitter.com/bDTTTgsUHc— Omaha Productions () September 12, 2023 Bills' kicker Tyler Bass' field goal excites 'ManningCast' BILLS CALLED BANK pic.twitter.com/FDPfEgIFtG— Omaha Productions () September 12, 2023 Garrett Wilson's highlight touchdown catch was a hit Peyton, Eli & Ryan Fitzpatrick are all of us reacting to that Garrett Wilson TD Catch pic.twitter.com/icZxSkuDqN— Omaha Productions () September 12, 2023 Tom Brady to the Jets? Peyton and Eli say no "Tom Brady going to the Jets would be illegal." pic.twitter.com/QJ3Mg1HRMJ— Omaha Productions () September 12, 2023 Peyton and Eli have their own way of showing brotherly love It's only Week 1 but Peyton and are making fun of each other in midseason form. pic.twitter.com/oiGoVWRnIp— Omaha Productions () September 12, 2023 Peyton shows off his singing voice to McEnroe We didn't have "Peyton singing" on our bingo card tonight. pic.twitter.com/i8ioiNUzqX— Omaha Productions () September 12, 2023 Peyton reacts to Rodgers' ankle injury "Holy cow! I cannot believe this."Peyton was shook by Aaron Rodgers' early injury. pic.twitter.com/rhmSXMW6O5— ESPN () September 12, 2023 Eli snubbed by Kentucky Derby invite Ouch, didn't get the invite to the Kentucky Derby... pic.twitter.com/eTKVZtJr8a— Omaha Productions () September 12, 2023 Peyton and Eli conduct interviews for third 'ManningCast' host You could say the auditions for a third ManningCast host did not go as expected. pic.twitter.com/dDfdblWpVm— Omaha Productions () September 5, 2023